| Rt Hon Charles Leslie Falconer, Baron Falconer of Thoroton | 9 May 2007 | 28 June 2007 |
| Rt Hon John Whitaker Straw | 28 June 2007 | 11 May 2010 |
| Rt Hon Kenneth Harry Clarke | 12 May 2010 | 4 September 2012 |
| Rt Hon Christopher Stephen Grayling | 4 September 2012 | 10 May 2015 |
| Rt Hon Michael Andrew Gove | 10 May 2015 | 14 July 2016 |
| Rt Hon Mary Elizabeth Truss | 14 July 2016 | 11 June 2017 |
| Rt Hon David Roy Lidington | 11 June 2017 | 8 January 2018 |
| Rt Hon David Michael Gauke | 8 January 2018 | 24 July 2019 |
| Robert James Buckland | 24 July 2019 | 15 September 2021 |
| Rt Hon Dominic Rennie Raab | 15 September 2021 | 6 September 2022 |
| Rt Hon Brandon Kenneth Lewis | 6 September 2022 | 25 October 2022 |
| Rt Hon Dominic Rennie Raab | 25 October 2022 | 21 April 2023 |
| Alexander John Gervase Chalk | 21 April 2023 | 5 July 2024 |