| Rt Hon Richard Austin Butler | August 1944 | May 1945 |
| Rt Hon Sir David McAdam Eccles | 1954 | January 1957 |
| Rt Hon Sir David McAdam Eccles | October 1959 | 1962 |
| Rt Hon Sir Edward Charles Gurney Boyle, bt | 1962 | October 1964 |
| Rt Hon John Haggitt Charles Patten | 11 April 1992 | 20 July 1994 |
| Rt Hon Gillian Patricia Shephard | 20 July 1994 | 5 July 1995 |
| Michael Andrew Gove | 12 May 2010 | 15 July 2014 |
| Rt Hon Nicola Ann Morgan | 15 July 2014 | 14 July 2016 |
| Rt Hon Justine Greening | 14 July 2016 | 8 January 2018 |
| Damian Patrick George Hinds | 8 January 2018 | 24 July 2019 |
| Gavin Alexander Williamson | 24 July 2019 | 15 September 2021 |
| Nadhim Zahawi | 15 September 2021 | 5 July 2022 |
| Rt Hon Michelle Emma May Elizabeth Donelan | 5 July 2022 | 7 July 2022 |
| Rt Hon James Spencer Cleverly | 7 July 2022 | 6 September 2022 |
| Rt Hon Christopher Laurie Malthouse | 6 September 2022 | 25 October 2022 |
| Gillian Keegan | 25 October 2022 | 5 July 2024 |
| Bridget Maeve Phillipson | 5 July 2024 |