| Rt Hon Dr Christopher Addison | June 1919 | April 1921 |
| Rt Hon Arthur Neville Chamberlain | 7 March 1923 | 27 August 1923 |
| Rt Hon Arthur Neville Chamberlain | 25 August 1931 | 5 November 1931 |
| Rt Hon Walter Elliot Elliot | May 1938 | May 1940 |
| Rt Hon Alfred Ernest Brown | 8 February 1941 | 11 November 1943 |
| Aneurin Bevan | July 1945 | January 1951 |
| Dr Gerard Folliott Vaughan | May 1979 | April 1982 |
| Kenneth Harry Clarke | 5 March 1982 | 1 September 1985 |
| Virginia Hilda Brunette Maxwell Bottomley | October 1989 | 11 April 1992 |
| Dr Brian Stanley Mawhinney | 11 April 1992 | 20 July 1994 |
| Jacqueline Jill Smith | 11 June 2001 | 13 June 2003 |