| Rt Hon Clement Richard Attlee | 1942 | 23 May 1945 |
| Rt Hon Robert Anthony Eden | 27 October 1951 | 6 April 1955 |
| Rt Hon Richard Austin Butler | 13 July 1962 | 18 October 1963 |
| Rt Hon Sir Richard Edward Geoffrey Howe | 24 July 1989 | 1 November 1990 |
| Rt Hon Michael Ray Dibdin Heseltine | 5 July 1995 | 2 May 1997 |
| Rt Hon John Leslie Prescott | 2 May 1997 | 27 June 2007 |
| Rt Hon Nicholas William Peter Clegg | 11 May 2010 | 8 May 2015 |
| Rt Hon Dominic Rennie Raab | 15 September 2021 | 6 September 2022 |
| Dr Th?r?se Anne Coffey | 6 September 2022 | 25 October 2022 |
| Rt Hon Dominic Rennie Raab | 25 October 2022 | 21 April 2023 |
| Rt Hon Oliver James Dowden | 21 April 2023 | 5 July 2024 |
| Angela Rayner | 5 July 2024 |