| Rt Hon Clare Short | 3 May 1997 | 12 May 2003 |
| Rt Hon Dr Valerie Ann Amos, Baroness Amos of Brondesbury | 12 May 2003 | 6 October 2003 |
| Rt Hon Hilary James Wedgwood Benn | 6 October 2003 | 28 June 2007 |
| Rt Hon Douglas Garven Alexander | 28 June 2007 | 11 May 2010 |
| Andrew John Bower Mitchell | 12 May 2010 | 3 September 2012 |
| Rt Hon Justine Greening | 4 September 2012 | 14 July 2016 |
| Rt Hon Priti Sushil Patel | 14 July 2016 | 8 November 2017 |
| Penelope Mary Mordaunt | 9 November 2017 | 1 May 2019 |
| Roderick James Nugent Stewart | 1 May 2019 | 24 July 2019 |
| Alok Kumar Sharma | 24 July 2019 | 13 February 2020 |
| Anne-Marie Belinda Trevelyan | 13 February 2020 | 2 September 2020 |