| Rt Hon Sir Spencer Compton Cavendish, Duke of Devonshire | 3 March 1900 | 11 August 1902 |
| Sir Charles Stewart Vane-Tempest-Stewart, Marquess of Londonderry | 1902 | 1905 |
| Rt Hon Prof Augustine Birrell | 10 December 1905 | 23 January 1907 |
| Rt Hon Reginald McKenna | 23 January 1907 | 12 April 1908 |
| Walter Runciman | 12 April 1908 | 23 October 1911 |
| Rt Hon Joseph Albert Pease | 23 October 1911 | 25 May 1915 |
| Arthur Henderson | 1915 | 1916 |
| Edward Frederick Lindley Wood | 1922 | 1924 |
| Rt Hon Hastings Bertrand Lees-Smith | 1931 | 1931 |
| Rt Hon Sir Donald Maclean | 25 August 1931 | 15 June 1932 |
| Rt Hon Oliver Frederick George Stanley | 1935 | 1937 |
| Rt Hon Sir James Richard Stanhope, Earl Stanhope | 1937 | 1938 |
| Herbrand Edward Dundonald Brassey Sackville, Earl de la Warr | 1938 | April 1940 |
| Rt Hon Richard Austin Butler | July 1941 | August 1944 |